When is it appropriate to use an open flame in the laboratory?

Using an open flame in the laboratory is appropriate when necessary for certain reactions, particularly those that require heating or the ignition of combustible materials. Certain chemical reactions and processes, such as organic synthesis, fuming processes, or when using specific reagents, may demand the application of an open flame to facilitate the desired chemical transformation.

It is imperative to ensure that all safety protocols are observed before using an open flame, including checking for the presence of flammable materials and ensuring that proper personal protective equipment is worn. The use of an open flame should always be a calculated decision, made only when it is essential for the experiment being conducted.